aβ 18 f nav brain pet data Search Results


18f av 1451 pet  (Danaher Inc)
86
Danaher Inc 18f av 1451 pet
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
18f Av 1451 Pet, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/18f av 1451 pet/product/Danaher Inc
Average 86 stars, based on 1 article reviews
18f av 1451 pet - by Bioz Stars, 2026-04
86/100 stars
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gemini tf 16 scanner  (Philips Healthcare)
90
Philips Healthcare gemini tf 16 scanner
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Gemini Tf 16 Scanner, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
gemini tf 16 scanner - by Bioz Stars, 2026-04
90/100 stars
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18 f-florbetapir pet imaging  (Siemens AG)
90
Siemens AG 18 f-florbetapir pet imaging
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
18 F Florbetapir Pet Imaging, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/18 f-florbetapir pet imaging/product/Siemens AG
Average 90 stars, based on 1 article reviews
18 f-florbetapir pet imaging - by Bioz Stars, 2026-04
90/100 stars
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aβ 18 f-nav4694  (Siemens AG)
90
Siemens AG aβ 18 f-nav4694
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ 18 F Nav4694, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aβ 18 f-nav4694 - by Bioz Stars, 2026-04
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aβ 18 f nav brain pet data  (MathWorks Inc)
93
MathWorks Inc aβ 18 f nav brain pet data
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ 18 F Nav Brain Pet Data, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
aβ 18 f nav brain pet data - by Bioz Stars, 2026-04
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aβ pet 18 f flutemetamol pet scans  (Danaher Inc)
86
Danaher Inc aβ pet 18 f flutemetamol pet scans
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ Pet 18 F Flutemetamol Pet Scans, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aβ pet 18 f flutemetamol pet scans/product/Danaher Inc
Average 86 stars, based on 1 article reviews
aβ pet 18 f flutemetamol pet scans - by Bioz Stars, 2026-04
86/100 stars
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aβ-pet [18f]azd4694  (Siemens AG)
90
Siemens AG aβ-pet [18f]azd4694
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ Pet [18f]Azd4694, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aβ-pet [18f]azd4694 - by Bioz Stars, 2026-04
90/100 stars
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florbetapir aβ tracer  (Avid Radiopharmaceuticals)
90
Avid Radiopharmaceuticals florbetapir aβ tracer
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Florbetapir Aβ Tracer, supplied by Avid Radiopharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
florbetapir aβ tracer - by Bioz Stars, 2026-04
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flortaucipir (ftp  (Eli Lilly)
90
Eli Lilly flortaucipir (ftp
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Flortaucipir (Ftp, supplied by Eli Lilly, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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flortaucipir (ftp - by Bioz Stars, 2026-04
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aβ-pet ([ 18 f]azd4694)  (Siemens Healthineers)
90
Siemens Healthineers aβ-pet ([ 18 f]azd4694)
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ Pet ([ 18 F]Azd4694), supplied by Siemens Healthineers, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aβ-pet ([ 18 f]azd4694) - by Bioz Stars, 2026-04
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18f-florbetapir (18f-av-45)  (Beijing Tiantan Biological)
90
Beijing Tiantan Biological 18f-florbetapir (18f-av-45)
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
18f Florbetapir (18f Av 45), supplied by Beijing Tiantan Biological, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aβ-binding radioligand amyvid  (Eli Lilly)
90
Eli Lilly aβ-binding radioligand amyvid
21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.
Aβ Binding Radioligand Amyvid, supplied by Eli Lilly, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aβ-binding radioligand amyvid - by Bioz Stars, 2026-04
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Image Search Results


21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.

Journal: Cells

Article Title: New Perspectives in Radiological and Radiopharmaceutical Hybrid Imaging in Progressive Supranuclear Palsy: A Systematic Review

doi: 10.3390/cells12242776

Figure Lengend Snippet: 21 articles published between 2017 and 2023 after application of the inclusion and exclusion criteria. a—years (age given as mean ± standard deviation, if not otherwise stated); AUC—Area Under the Curve; AD—Alzheimer’s Disease; BPND—Non-Displaceable Binding Potential; CBD—Corticobasal Degeneration; CBS—Corticobasal Syndrome; CSF—Cerebrospinal Fluid; CT—Computed Tomography; DLB—Dementia with Lewy Bodies; DTI—Diffusion Tensor Imaging; FA—Fractional Anisotropy; f—Female; GE—General Electric; GM—Gray Matter; HC—Healthy Control; MCI—Mild Cognitive Impairment; MD—Mean Diffusivity; min—Minutes; MMSE—Mini-Mental State Examination; MoCA—Montreal Cognitive Assessment; MRI—Magnetic Resonance Imaging; MPRAGE—Magnetization Prepared Rapid Gradient Echo; NBS—Network-Based Statistics; NfL—Neurofilament Light; ODI—Orientation Dispersion Imaging; PD—Parkinson’s Disease; PET—Positron Emission Tomography; PSP—Progressive Supranuclear Palsy; PSPRS—Progressive Supranuclear Palsy Rating Scale; RAVLT—Rey Auditory Verbal Learning Test; ROI—Region of Interest; SUV—Standardized Uptake Value; SUVR—Standardized Uptake Value Ratio; UPDRS—Unified Parkinson’s Disease Rating Scale; WM—White Matter.

Article Snippet: Whitwell 2018 [ ] (7) , - 30 PSP (median 70 a, range 65–73 a, 18 f) - 64 age- and gender-matched Aβ-negative HC , [18F]AV-1451 PET , - GE Healthcare PET/CT (GE Healthcare, Waukesha, WI, USA). A bolus injection of 370 MBq of [18F]AV-1451, followed by a 20 min PET acquisition 80 min after injection. Subjects had MPRAGE sequences performed within 48 h of the PET scans. , - Higher AV-1451 SUVR in AD-related regions (middle temporal gyrus, inferior temporal gyrus, fusiform, amygdala, entorhinal cortex and parahippocampal gyrus) was associated with higher AV-1451 SUVR in PSP-related regions (midbrain, globus pallidum, thalamus, dentate nuclei of the cerebellum and motor cortex). Higher PiB SUVR was not significantly associated with AV-1451 SUVR in AD- or PSP-related regions. PiB(−) group showed WM atrophy in midbrain and superior cerebellar peduncles, and GM atrophy in frontal regions and striatum vs. HC. PiB(+) group showed WM atrophy in midbrain and GM atrophy in frontal regions and striatum vs. HC. Aβ deposition occurs in PSP predominantly as an age-related phenomenon, with little evidence that Aβ and PHF-tau play a significant role in neurodegeneration in PSP..

Techniques: Standard Deviation, Binding Assay, Tomography, Imaging, Dispersion, Computed Tomography, In Vivo, Transmission Assay, Injection, Functional Assay, Positron Emission Tomography, Marker, Expressing, Variant Assay, Positron Emission Tomography-Computed Tomography, Activity Assay